AboutNR

You have discovered the scientifically-backed information resource on a next-generation form of vitamin B3 called NR (nicotinamide riboside).

This astonishing nutrient is currently being studied by scientists worldwide for its ability to work at the cellular level to:

  • Activate anti-aging mechanisms*
  • Enhance energy metabolism*
  • Protect against oxidative stress*

With the help of some of the world’s leading scientific researchers, we are committed to delivering you the latest discoveries and expert discussions that surround NR.

Our goal is to inform and empower you with useful information about NR as you consider your own health-longevity.

 


 
Trending Articles  

Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats

Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats

Published in: Journal of the International Association for the Study of Pain (PAIN) Injury to sensory afferent nerves may contribute to the peripheral neuropathies that develop after administration of chemotherapeutic agents. Manipulations that increase levels of nicotinamide adenine dinucleotide (NAD+) can protect against neuronal injury. This study examined whether nicotinamide riboside (NR), a next-generation form

No evidence that NR or NAD+ precursors cause brain cancer

No evidence that NR or NAD+ precursors cause brain cancer

Written by: Amy Boileau, Ph.D., R.D. In a paper published in the journal PNAS, researchers at Washington University School of Medicine in St. Louis reported that glioblastoma tumors over-produce NAMPT, an enzyme which is involved in the creation of NAD+. The researchers used animal and cell models to demonstrate that if the activity of this

An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma

An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma

Published in PNAS. Accumulating evidence suggests cancer cells exhibit a dependency on metabolic pathways regulated by nicotinamide adenine dinucleotide (NAD+). Nevertheless, how the regulation of this metabolic cofactor interfaces with signal transduction networks remains poorly understood in glioblastoma. Here, we report nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting step in NAD+ synthesis, is highly expressed in glioblastoma

Age-Associated Changes In Oxidative Stress & NAD+ Metabolism In Human Tissue

Age-Associated Changes In Oxidative Stress & NAD+ Metabolism In Human Tissue

Published in PLOS One. We need NAD+ in our cells to make an enzyme called PARP, which fights oxidative damage and helps keep our DNA in good repair. We also need NAD+ to support the activities of enzymes called sirtuins, the so-called “longevity enzymes”. It’s been established in rodents that there are links between age-related

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

Published in Nature Communications. Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we determine the time and dose-dependent effects of NR on blood NAD+ metabolism in humans. We report that human blood NAD+ can rise as much as 2.7-fold with a single oral dose of NR in a pilot study

References

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.