Published Research

Published Research Abstract Briefs  

Age-Associated Changes In Oxidative Stress & NAD+ Metabolism In Human Tissue

Age-Associated Changes In Oxidative Stress & NAD+ Metabolism In Human Tissue

Published in PLOS One. We need NAD+ in our cells to make an enzyme called PARP, which fights oxidative damage and helps keep our DNA in good repair. We also need NAD+ to support the activities of enzymes called sirtuins, the so-called “longevity enzymes”. It’s been established in rodents that...
NR opposes type 2 diabetes & neuropathy in mice

NR opposes type 2 diabetes & neuropathy in mice

Published by Nature.com. Millions of people struggle with obesity as well as pre-diabetes or diabetes. These metabolic disorders are often associated with poor glycemic control which can lead to diabetic nerve damage (insensitivity to heat and touch). It’s been recently discovered that NR can...
Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk

Published in the Journal of Nutrition. In this collaborative study, researchers wanted to determine the concentration of NAD+ build-block vitamins (including NR) in samples of raw milk from individual cows and from commercially available cow milk. They also wanted to assess the stability of NR...
Safety assessment of NR, a form of vitamin B3

Safety assessment of NR, a form of vitamin B3

Published in Human & Experimental Toxicology. Nicotimamide riboside (NR) is a naturally occurring form of vitamin B3, present in trace amounts in some foods. As with niacin, it has been shown to be a precursor to the formation of NAD+. The safety of Niagen®, a synthetic form of NR, was...